It is a supplement that is formed in the body by an enzymatic reaction between ATP (adenosine triphosphate) and methionine . It was discovered in 1952 in Italy and has been extensively researched and manufactured. SAMe works closely with folic acid and vitamin B- 12 and functions as a methyl donor. This nutrient transports and donates methyl molecules necessary to facilitate the production of DNA and essential molecules for the functioning of the nervous system and normal psychological function. Also for the normal formation of red blood cells. Format: Box with 50 capsules. How to use: As a dietary supplement, take 1 capsule 1 or 2 times a day, preferably on an empty stomach. Ingredients: S-Adenosyl Methionine (SAM-e)...200.0 mg, Vitamin B9 (Folic Acid)...100.0 µg, Vitamin B6 (Pyridoxine)...1.0 mg, Vitamin B12 (0.1% Cyanocobalamin)...0.5 µg , Microcrystalline cellulose (thickener), Croscarmellose Sodium, * Magnesium stearate (anti-caking agent), Silicon dioxide (Anti-caking agent), Gelatin capsule. Nutritional information: For 1 caps S-Adenosyl-L-Methionine disulfate tosylate 200mg Vitamin B6 (QUALI-B) 1mg Vitamin B12 (QUALI-B) 0.2 mg Vitamin B9 (QUALI-B) 0.1mg Nutritional information 100 grams Energetic value 328.03 kj - 79.58 kcal fats 5.36g of which saturates 5.33g carbohydrates 8.50 grams of which sugars 0 gr Proteins 0 gr